Expansion Systems

Stem cell research and its applications has been significantly limited by the very low availability of adult stem cells. Classic methods for the expansion of stem cells have proven costly with very low efficiency.

Cambridge Bioscience offers NANEX™, a nanofiber-based scaffold for the efficient culture and expansion of hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) from human bone marrow and umbilical cord blood ex vivo. This product expands HSCs and HPCs with superior performance and consistency than any other product on the market.

The NANEX™ cell culture substrate is a nanofiber-based 3D scaffold that partially mimics the bone marrow stem cell niche. When used in combination with serum-free medium and a cocktail of growth factors, the NANEX™ scaffold can facilitate the proliferation of HSCs and HPCs without significant loss of the stem cell phenotype. This system maintains exceptionally high purity (over 3 times higher than tissue treated culture plates and poly-amine surfaces) and exceptional yield with each kit producing over 10 million CD34+ cells from less than 100,000 cells within 10 days from a cord blood source and significant fold induction from others. These features make this system ideal for large scale studies by eliminating donor variability and for translational research

Benefits of Using NANEX™
• Significantly expands HSCs & HPCs
Yields at least 3 times more CD34+ cells over other expansion products on the market
Each kit yields over 10 million CD34+ from less than 100,000 cells within 10 days from a cord blood source and significant fold induction from others eliminating donor variability
• Creates an in vivo-like culture environment
Mimics the bone marrow niche
• Maintains high HSCs & HPCs purity
At least 3 times higher than tissue treated culture plates and poly-amine surfaces on the market
• Easy handling and cell harvesting process
• Expanded cells maintain multipotency and colony forming potential
• Ideal for large scale studies and translational research

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Featured products within Expansion Systems