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Endothelin

Endothelins are proteins that constrict blood vessels and raise blood pressure. There are three isoforms the most common of which is ET-1, which is formed by cleavage of the proenzyme big endothelin by endothelin converting enzyme-1. Elevated levels of endothelin have been detected in patients suffering from myocardial infarction, pulomonary hypertension and cardiogenic shock.

Cambridge Bioscience offers endothelin antibodies, proteins and peptides.

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