Chloride Channels

Cambridge Bioscience, through our collaboration with ChanTest, offers access to screening services to the following chloride channel targets:

CFTR
Gene Name: CFTR
Validated Assay/Platform: IonWorks Quattro™ & QPatch HT
Description: The human CFTR gene encodes the pore-forming subunit of the cAMP-regulated epithelial chloride channel associated with cystic fibrosis.

CLC-1
Gene Name: CLCN1
Validated Assay/Platform: PatchXpress® & QPatch HT
Description: The human CLCN1 gene encodes the pore-forming subunit of a voltage-gated chloride channel highly expressed in skeletal muscle.

CLC-2
Gene Name: CLCN2
Validated Assay/Platform: PatchXpress®
Description: The human CLCN2 gene encodes the pore-forming subunit of a voltage-gated chloride channel expressed in intestinal epithelia and the central nervous system

Platforms Available
Cambridge Bioscience, through our collaboration with ChanTest, offers access to the widest range of screening platforms, from manual patch clamp up to the most recent innovations in automated electrophysiology, allowing you to select the right balance of speed, throughput and data quality to suit your needs.
To find out more about each of these platforms, please Click Here

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To discuss an ion channel screening project, please contact our experienced team by Clicking Here