Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Comprehensive Epigenetic Profiling and Screening Services
Ion Channel Screening & Profiling Services

Acid-Sensing Channels

Cambridge Bioscience, through our collaboration with B'SYS, offers access to screening services for the following acid sensing channel targets:

ASIC1a (long/short), ASIC1b
Gene Name: ACCN2
Description: The human ACCN2 gene encodes the pore-forming subunit of ASIC1a, a proton-activated channel, permeable to both Na+ and Ca2+ ions. ASIC1a channels are widely expressed in the neurons of the peripheral and central nervous systems and are therapeutic targets in pain and neurodegenerative diseases.

ASIC2a
Gene Name: ACCN1 
Description: The human ACCN1 gene encodes the pore-forming subunit of ASIC2a, a proton-activated, Na+-permeable channel. ASIC2a channels are widely expressed in sensory neurons of the peripheral and central nervous systems and are therapeutic targets in pain and neurodegenerative diseases.

ASIC3
Gene Name: ACCN3
Description: The human ACCN3 gene encodes the pore-forming subunit of ASIC3, a proton-activated, Na+-permeable channel. ASIC3 channels are expressed primarily in dorsal root ganglion neurons and are therapeutic targets in pain and inflammation.

Speak to a Specialist
To discuss an acid sensing screening project with one of our specialists, please Click Here

Contact Our B'SYS Specialist, Vashu