Product Category: Cancer Research
T-Cell Immune Suppression- Myeloid-Derived Suppressor CellsMyeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection. MDSCs have been shown to suppress the anti-tumor response to cancer, enabling cancers to evade the body's immune system. BioLegend offers a range of purified antibodies and fluorescent conjugates, cytokines and chemokines to study MDSCs. Click here to learn more  OxiSelect Protein Carbonyl Assay KitsCell Biolabs OxiSelectTM Protein Carbonyl Assay Kits Cell Biolabs’ OxiSelect™ Protein Carbonyl Assay Kits provide rapid, efficient methods for detection of protein carbonyls. Three assay formats are available: immunoblot, ELISA or spectrophotometer. All formats are suitable for use with purified protein, plasma, serum, or cell lysate samples. Protein Carbonyl ELISA Kit Protein Carbonyl Immunoblot Kit Click here for more information.  SBIs Cancer microRNA qPCR ArraySimultaneously profile 95 different MicroRNAs known to be involved in apoptosis, differentiation and Cancer
SensoLyte™ 520 HDAC Activity Assay Kit FluorimetricHistone deacetylase (HDAC) enzymes modulate gene expression through the deacetylation of lysine residues on histone proteins and act as transcriptional repressors of genes. Based on their role in cell cycling, apoptosis and differentiation, HDACs have been chosen as therapeutic targets for the treatment of cancer and neurodegenerative diseases. The SensoLyte™ 520 HDAC Activity Assay Kit from AnaSpec, provides a convenient, two-step homogeneous procedure for measuring HDAC activity using a cell-permeable fluorogenic substrate. Without a time-consuming cell extraction step, this assay can be used to measure HDAC activity directly in cell culture in a 96-well plate. This kit can also be used for high throughput screening of HDAC inhibitors using extracts or purified enzymes. AnaSpec also offers the SensoLyte™ 440 HDAC Activity Assay Kit as a cost-effective solution for moderate sensitivity. Monosan Cytokeratin AntibodiesIn the field of diagnostic medicine, antibodies against cytokeratins are instrumental in the distinction of epithelial malignancies from sarcomas and lymphomas of various types. Cytokeratin subtype expression patterns are now also being used in the distinction of different types of epithelial malignancies. Cytokeratin antibodies are of assistance in the differential diagnosis of tumours using immunohistochemistry on tissue sections, and increasingly in cytopathology and flow cytometric assays.  Large scale, quantitative tools for protein biomarker research from OriGeneThe new ProteoScan Cancer Lysate Arrays from OriGene are high-density reverse-phase protein arrays (RPPA, or RPA) assembled from 432 cancer and normal tissue protein lysates. With protein-specific antibodies, ProteoScan Cancer Lysate Arrays enable quantitative identification and validation of protein expression profiles and post-translation modifications associated with 11 types of cancer.
Please click here for more information.  TissueScan: qPCR ArraysValidate Biomarkers Across Hundreds of Tissues in Less Than 2 Hours TissueScan is a unique qPCR array of first-strand cDNA from hundreds of clinical tumor samples. It provides fast and accurate gene expression profiling across a large number of cancer patient samples. High-quality cDNAs were prepared from well-documented cancer biopsy samples, normalized and assembled into ready-to-use gene expression panels. This alleviates the tedious work of sample collection and RNA/cDNA preparation, while facilitating quick and reliable profiling of gene expression levels across cancer progression stages. TissueScan combines the high sensitivity and specificity of the RT-PCR methodology with a well-designed multi-sample format. It is an excellent tool for validation of potential cancer markers such as those obtained by microarray analysis.  HNP1-3 and Screening of Colorectal DiseaseThe new HNP1-3 ELISA kit is a useful tool as a non invasive method to measure levels of HNP1-3 in stool samples for the diagnosis of colorectal diseases. Special features of the assay:
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