Product Category: Apoptosis
Lactadherin detects earliest stages of ApoptosisPhosphatidylserine appears on the outer membrane leaflet of cells undergoing programmed cell death and marks those cells for clearance by macrophages. Macrophages secrete lactadherin, a PS-binding protein, which tethers apoptotic cells to macrophage integrins.HTI have recently introduced fluorescein-labelled bovine lactadherin which can now be used to detect PS exposure by flow cytometry and confocal microscopy.  Autophagy Products from AbgentAbgent has the most extensive collection of autophagy antibodies. From the hallmark autophagy antibody APG8 (MAPLC3) to the newest autophagy antibodies such as LAMP and APG1, count on Abgent to find the most relevant, qualified antibodies for autophagy research.
 New Antibodies for Researchers using the Zebrafish ModelZebrafish (Danio rerio) have become an increasingly favoured vertebrate model for studying genes and gene function. One of the reasons for this is that zebrafish embryos are completely transparent. This makes them ideal for studying developmental processes in real time, allowing the study of vertebrate development and for understanding human disease processes.
For further information please visit the following site  Apoptosis Research Tools BrochureImgenex have a growing portfolio of antibodies and inhibitors to proteins and processes involved in apoptosis signaling encompasses a wide variety of techniques including flow cytometry, western blot analysis, immunoprecipitation, immunohistochemistry, immunofluorescence micro-scopy, and blocking apoptosis. Additionally, Imgenex have recently launched RNA interference (RNAi/siRNA) tools to knock down genes involved in apoptosis. These siRNAs can be used to transiently silence a specific gene in cell lines or to generate stable knockdown cell lines. To request your copy of the Imgenex Apoptosis Research Tools Brochure, please click here  BioVision Annexin V Apoptosis KitsBioVision's Annexin V conjugates are engineered to produce enhanced, photostable fluorescent signals. The extremely simple Annexin V assay takes only 10 minutes. Results can be analysed by flow cytometry or fluorescence microscopy.  CaspGLOW in situ Caspase Staining KitsCaspGLOW In situ Caspase Staining Kits utilise potent caspase inhibitors conjugated to FITC or rhodamine as fluorescent markers. The inhibitors are cell permeable, non-toxic, and irreversibly bind to activated caspases in apoptotic cells. Directly visualise activated caspases using fluorescence microscopy, flow cytometry or a fluorescent plate reader.  New Generation of Caspase Inhibitors Q-VD-OPHBioVision is now offering Q-VD-OPH the next generation of caspase inhibitors. Studies have shown that Q-VD-OPh is significantly more effective in preventing apoptosis than the widely used inhibitors, ZVAD-fmk and Boc-D-fmk. It is also equally effective in preventing apoptosis mediated by caspase 9/3, caspase 8/10, and caspase 12, the three major apoptotic pathways. An additional benefit is that Q-VD-OPH is non-toxic to cells even at extremely high concentrations.
Cell Biolabs Anoikis AssaysApoptosis resulting from the loss of adhesion to the ECM is known as anoikis. Anoikis is involved in the physiological processes of tissue renewal and cell homeostasis. Cell Biolab's CytoSelect 24-Well Anoikis Assay allows you to quantify and monitor anoikis in cells using a 24-well Poly-HEMA precoated plate. Live cells can be viewed under a microscope and quantified on a plate reader by MTT (colorimetric) or Calcein AM (fluorometric); both reagents are included in the kit. Dead cells are detected with the red EthD-1 reagent, also included.
 |
|
|
