Product Category: GPCR Products

GPCR Expressing Cell Lines and Membranes

Our GPCR (G protein-coupled receptor) targets are stably expressed in recombinant cell lines, providing high expression, and low background.

We offer researchers cell lines for different budgets.

Our replicating GPCR cells come with or without a modified CNG tag. These cell lines express a modified CNG (cyclic-nucleotide gated) channel along with several different GPCRs. CNG channels are activated by intracellular cAMP causing cellular depolarization, which can be detected with membrane potential (MP) dyes (and calcium dyes) on a FLIPR.

To order these cell lines, you will also need to order the Membrane Potential Dye Kits (Cat # CT-80500201).