Product Category: Protein Analysis
Biological Application of FRET – Protease DetectionIn recent years, FRET based assays have found broad applications, one of which is the detection of protease activity. Proteases play key roles in protein activation, cell regulation and signaling, as well as in the generation of amino acids for protein synthesis or utilization in metabolic pathways. Cathepsins D, S  Heavy isotope labeled full-length human protein SRM/MRM Mass Spec StandardsIn a "first of its kind" launch OriGene now offers the service to generate Mass Spectrometry (MS) standards for 5,000 human proteins. Produced in human HEK293T cells and labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, the full length proteins with appropriate post-translational modifications are the best identification and quantification standards.Heavy isotope labeled human proteins are ideal internal standards for SRM/MRM (single reaction monitoring, multiple reaction monitoring) mass spectrometry analyses for high throughput proteomics and clinical biomarker research.
For further details please click here.  Easy Effective Protein Cleavage Using Progenta AALSThe Progenta Anionic Acid Labile Surfactants (AALS) have been engineered to provide a safe, robust alternative to detergents (e.g. SDS) that are commonly used in proteomics work, but that negatively impact subsequent analysis by mass spectrometry. While SDS and other detergents can improve protein solubility, they can be very difficult to remove during sample prep and purification of the protein sample. These bound detergents can cause significant impairment of protein analysis by mass spectrometry, as the surfactants can suppress analyte ion signal, promote analyte adduct formation, and present as contaminants during the analysis.
 |
|
|
