Product Category: Metabolism

15% Off Hycult Biotech FABP Products

15% Discount On All Hycult Biotech FABP Products

We are delighted to offer a 15% discount on all Fatty Acid Binding Protein (FABP) products from our partner Hycult Biotech. FABP’s are small intracellular cytoplasmic proteins with a high degree of tissue specificity that bind long chain fatty acids.

Our products include many of the different types of FABP including H-FABP, I-FABP and L-FABP. This offer includes ELISA Kits, Proteins and Monoclonal and Polyclonal Antibodies. 

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OxiSelect Protein Carbonyl Assay Kits

Cell Biolabs OxiSelectTM Protein Carbonyl Assay Kits
The most common products of protein oxidation in biological samples are the carbonyl derivatives of Pro, Arg, Lys and Thr residues. Such derivatives are chemically stable and serve as markers for oxidative stress in most types of reactive oxygen species.

Cell Biolabs’ OxiSelect™ Protein Carbonyl Assay Kits provide rapid, efficient methods for detection of protein carbonyls. Three assay formats are available: immunoblot, ELISA or spectrophotometer. All formats are suitable for use with purified protein, plasma, serum, or cell lysate samples.

Protein Carbonyl ELISA Kit
• Sensitive: Detects samples as low as 10 μg/ml
• Greater Sample Retention: No concentration/TCA precipitation steps

Protein Carbonyl Immunoblot Kit
• No Molecular Weight Shift: DNPH Derivatization after immunoblotting allows direct comparison of oxidized and non-oxidized protein fingerprint

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*NEW* Complex I Microplate Assays

Mitosciences have introduced two new Complex I Microplate Assay kits to determine activity/quantity of mitochondrial OXPHOS Complex I (NADH dehydrogenase or NADH ubiquinone oxidoreductase).

• Complex I Enzyme Activity Microplate Assay Kit
• Complex I Protein Quantity Microplate Assay Kit

For further details please click here

MetaPath™ Multiplex Microplate Arrays

MetaPath™ arrays are built on the well-established sandwich ELISA concept. Multiplex arrays extend this concept to very high-throughput by spotting the capture antibodies in arrays on the bottom of 96-well plates. Detector antibodies with enzyme-linked tags are then added in one solution, and the relative amount of each target is read by an imager.

Catalogue No. MSX41: Quantitative analysis of mitochondrial Complex I, Complex IV, PDH and Frataxin.
Catalogue No. MSX42: Quantitative analysis of mitochondrial MCAD, SCHAD, TFP and Frataxin.

Further information on these MetaPath™ arrays can be found here.

Fatty Acid Metabolism Kits

Fatty acid binding protein (FABP) is a cytoplasmic component of fatty acid metabolism and marker of stress. Hycult Biotech produce kits for specific isoforms of FABP, providing a rapid colourimetric way of determining FABP levels in serum and plasma.

• Suitable for endogenous protein
• Non radioactive- Colourimetric detection
• Flexible- Use only the wells you need-save the rest
• Limits of detection data available
• Use on Culture Media, Serum, Plasma and Urine
• Kits for Multiple FABP isoforms: H-FABP, L-FABP, B-FABP,M-FABP and E-FABP

Adiponectin Antibodies

Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.

Adipocyte Related Products

Adiponectin is a serum protein produced and secreted exclusively by adipose tissues. Unlike insulin and leptin, adiponectin levels in plasma remain constant throughout the day and are not acutely affected by food intake.

Resistin face is another hormone secreted by adipocytes that acts on skeletal muscle myocytes, hepatocytes, and adipocytes themselves, where it is suggested to reduce insulin sensitivity leading to type 2 diabetes.

Leptin is the protein product of ob gene in mice and is involved in appetite Visfatinis considered a new member of the adipokine family. It is highly expressed in visceral fat and whose blood levels correlate with obesity.