Welcome to the Cambridge BioScience Drug Discovery Focus page. Here we bring you details of our latest most exciting and innovative products for your drug discovery research.

Cambridge BioScience now offer the most complete range of ion channel screening services to our customers throughout Europe. ChanTest are the World's leading provider of ion channel screening services. Their focus is on ion channels that may be either deliberate therapeutic targets or unintended targets that can result in unwanted side effects.

In addition to a full range of cardiac safety services, ChanTest is now building a major new battery of ion channel cell lines that have been validated across a range of ion channel screening platforms including IonWorks and Patch Express.

Click here for more information about the services available.

We now offer a broad range of GPCR expressing cell lines, and related membrane extracts developed by Applied Cell Sciences.

With more than 30 unique cell lines developed to-date and many more to follow, ACS aim to become one of the leading providers of GPCR reagents and tools for the GPCR screening market. Recent additions include GPR119 a target linked to diabetes and a particularly challenging cell line to develop.

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Expanding our range of human cancer biospecimens, we now represent Conversant Healthcare Systems throughout Europe.

Conversant provides human cancer blood specimens to academic and commercial researchers These are high quality cancer specimens matched with in-depth, privacy-protected clinical information - giving researchers a critical tool for the development of diagnostic tests, prognostic indicators, and targeted therapeutics.

Follow this link for further information

Expanding our other human tissue procurement capabilities, Cambridge BioScience has recently been appointed as the European distributor for PrecisionMed Inc..

PrecisionMed specialize in the collection biological fluids from donors with important neurological diseases including Alzheimer's Disease, depression, schizophrenia, bipolar disorder and Multiple Sclerosis. In addition they have large numbers of control samples for use in comparative studies.

Sample types available include serum, plasma, cerebrospinal fluid (CSF) as well as DNA and RNA preparations.

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Cambridge BioScience has recently been appointed as the exclusive European distributor for Cytomyx LLC.

Cytomyx operates one of the world's leading biorepositories and offers its clients access to high quality, ethically donated human biospecimens. The biorepository contains over 140,000 samples, with extensive representation of both normal and diseased tissues.

In addition to licensing tissue samples, Cytomyx is also able to provide high quality derivatives products, including RNA and DNA, as well as tissue microarrays and custom IHC services.

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GFC-Arrays are sets of transfection ready cDNA plasmids delivered in 384 well plate format, and optimised for immediate use in high throughput genome-wide cellular assays.

• simultaneously investigate thousands of genes
• instantly query the role of over-expressed proteins
• evaulate the causation role of genes on disease models, dont just rely on correlation data from transcript profiling
• based on Origene's TrueClone collection

GFC Arrays are available to study transcription factors, protein kinases, druggable genes, transmembrane proteins, and for screening.

click here to request further information on available arrays, and here for the GFC-Arrays product manual