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Welcome to the Cambridge BioScience Antibody portal. Please use the PRODUCT SEARCH facility to locate the antibody you are looking for. (Search Tip: search for Claudin instead of Anti-Claudin)

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HD3, CHD7 & CHD9/CReMM are members of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and play a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain.

CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes. Alternate names for CHD3 include chromodomain-helicase-DNA-binding protein 3, ATP-dependent helicase CHD3, Mi2 autoantigen 240 kDa protein, Mi2-alpha, zinc-finger helicase, hZFH, and ZFH.

CHD3 Antibody A301-219A Applications: WB, IP Qty: 0.1 ml Price: £207
CHD3 Antibody A301-220A Applications: IP Qty: 0.1 ml Price: £207

THEN WE HAVE THE ANTIBODIES FOR YOU!
Dendritics have generated a large variety of monoclonal antibodies to facilitate the characterisation of Dendritic Cell phenotype and function, in the steady-state, in animal models, and in human disease.

These high- quality antibodies have been validated by numerous publications and can be used for FACS analysis, ELISA, cell depletion, or immunochemistry.

PLUS key antibodies have also been optimised for immunohistochemistry on paraffin -embedded tissue to allow studies of archived clinical samples.

All antibodies are available in the basic purified format, with key antibodies available as Alexa-488, Alexa-546 or biotin conjugates.

For further product, ordering and price information click here.

• DC subtypes
• C- type lectin receptors
• Toll - like receptors
• DC migration
• Cytokines and Receptors
• Antigen processing/ presentation, allergy

LEAF Purified Antibodies for Functional Analyses

BioLegend’s LEAF (Low Endotoxin, Azide-Free) purified antibodies are specifically designed for functional analyses, providing the most accurate results with minimal negative effects. LEAF purified antibodies contain no preservative, are 0.2 µm filter sterilised, tested for sterility, and endotoxin level is < 0.1 EU/ µg of the protein (<0.01 mg/µg of the protein) as determined by the LAL test.

More than 200 antibodies are available in the LEAF format.
Please click here to enquire about your antibody of interest.

StressXpress is a range of highly sensitive ELISA assays for Heat Shock Proteins from Stressgen Bioreagents.

The range includes HSP27, HO-1, Hsp60, Hsp70, Hsp70B, Hs 90 as well as many related kits.

For further product, ordering and price information here.

The SouthernBiotech range of conjugated polyclonal second step antibodies is available exclusively from Cambridge BioScience.

For a full listing please click here

Need to eliminate a specific populations of cells from a mix of cell types?

Immuno-targeted toxins are the answer!

Available preconjugated to a range of primary antibodies or as "second immunotoxins" (secondary conjugates) which allow users to convert their own primary antibodies into specific cytotoxic tools.

Click here for more information

Previous Antibody Portal News items can be found here